Dmytro Strilets

Title

Novel dynamic frameworks targeting multidrug-resistant and/or WHO priority pathogen Acinetobacter baumannii

Supervisor

Prof. Stéphane Vincent

Research center

NAMUR RESEARCH INSTITUTE FOR LIFE SCIENCES

Research start date

01.09.2022

Description

Acinetobacter baumannii is a Gram-negative bacterium ranked as a top critical priority by both WHO and CDC due to resistance to last-resort antibiotics. New alternative therapies are therefore urgently required to combat this increasingly resistant pathogen. Classical strategies to develop new antibiotics have been impaired by both the lack of novel central scaffolds and by the rapid emergence of bacterial resistance. Moreover, the concept of personalized medicine is rapidly emerging, thus opening the search for novel personalized antibacterial agents. The latter would lower the side-effects, decrease or delay the resistance processes and preserve the host microbiota.

The TADAM project proposes to explore a novel way to discover and develop antibacterial agents specifically directed towards A. baumannii. This interdisciplinary project is based on the development of dynamic materials (also called DCFs).

Publications

Strilets, D., Cerneaux, S., Barboiu, M. Enhanced Desalination Polyamide Membranes Incorporating Pillar [5] arene through in‐Situ Aggregation‐Interfacial Polymerization‐isAGRIP. ChemPlusChem, 2021, 86(12), 1602-1607
Strilets, D., Fa, S., Hardiagon, A., Baaden, M., Ogoshi, T., Barboiu, M. Biomimetic Approach for Highly Selective Artificial Water Channels Based on Tubular Pillar [5] arene Dimers, Angewandte Chemie International Edition, 2020, 59(51), 23213-23219

Name

Dmytro Strilets

Birthdate

27 years old

Country

Ukraine

Contact email

qzlgeb.fgevyrgf@hanzhe.or

Linkedin

https://linkedin.com/in/dmytro-strilets-a65239242

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska Curie grant agreement No 101034383

Caroline Vliegen

C2W Project Manager

vasb@pbzrgbjnyybavn.rh
Place du Parc, 22 |7000 Mons |Belgium